MGI MouseCyc MP annotations for DENOVOPURINE2-PWY

MGI MouseCyc MP annotations for DENOVOPURINE2-PWY: purine nucleotides de novo biosynthesis I

Roles of genes might be detected in a summary/comparison table of high level MP categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";

Compare annotations to MP categories for DENOVOPURINE2-PWY.

Entry indicates that gene is in this pathway.
Colored entries indicate MP annotation.

ID	Term	1190002A17Rik	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9
MP:0005385	cardiovascular system phenotype	1190002A17Rik	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9
MP:0005384	cellular phenotype	1190002A17Rik	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9
MP:0005381	digestive/alimentary phenotype	1190002A17Rik	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9
MP:0005379	endocrine/exocrine gland phenotype	1190002A17Rik	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9
MP:0005378	growth/size phenotype	1190002A17Rik	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9
MP:0005397	hematopoietic system phenotype	1190002A17Rik	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9
MP:0005376	homeostasis/metabolism phenotype	1190002A17Rik	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9
MP:0005387	immune system phenotype	1190002A17Rik	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9
MP:0005373	lethality-postnatal	1190002A17Rik	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9
MP:0005374	lethality-prenatal/perinatal	1190002A17Rik	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9
MP:0005372	life span-post-weaning/aging	1190002A17Rik	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9
MP:0005370	liver/biliary system phenotype	1190002A17Rik	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9
MP:0005369	muscle phenotype	1190002A17Rik	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9
MP:0003631	nervous system phenotype	1190002A17Rik	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9
MP:0005395	other phenotype	1190002A17Rik	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9
MP:0005367	renal/urinary system phenotype	1190002A17Rik	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9
MP:0005389	reproductive system phenotype	1190002A17Rik	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9
MP:0005390	skeleton phenotype	1190002A17Rik	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9
MP:0002006	tumorigenesis	1190002A17Rik	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9
MP:0005391	vision/eye phenotype	1190002A17Rik	Adsl	Adss	Adssl1	Ak1	Ak2	Ak3	Ak3l1	Ak5	Ak7	Atic	Gart	Gmps	Guk1	Ifnar1	Impdh1	Impdh2	Mpp5	Nme1	Nme2	Nme3	Nme4	Nme5	Nme6	Nme7	Paics	Pfas	Ppat	Rp2h	Rrm1	Rrm2	Rrm2b	Taf9

Full set of annotations for DENOVOPURINE2-PWY

ID	Term	Mouse gene	Alleles	Background	Color Key
MP:0004392	abnormal CD8-positive T cell physiology	Ifnar1	Ifnar1^tm1Agt/Ifnar1^tm1Agt	involves: 129S2/SvPas * 129S6/SvEvTac	color key
MP:0005069	abnormal NK cell physiology	Ifnar1	Ifnar1^tm1Agt/Ifnar1^tm1Agt	involves: 129S2/SvPas	color key
MP:0002954	abnormal aerobic energy metabolism	Ak1	Ak1^tm1Bew/Ak1^tm1Bew	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0001648	abnormal apoptosis	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0002191	abnormal artery morphology	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0005265	abnormal blood urea nitrogen level	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0000662	abnormal branching of the mammary ductal tree	Nme1	Nme1^tm1Jyd/Nme1^tm1Jyd	129-Nme1	color key
MP:0005328	abnormal circulating creatinine level	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0000199	abnormal circulating serum albumin level	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0003009	abnormal cytokine secretion	Ifnar1	Ifnar1^tm1Agt/Ifnar1^tm1Agt	involves: 129S2/SvPas	color key
MP:0002376	abnormal dendritic cell physiology	Ifnar1	Ifnar1^tm1Agt/Ifnar1^tm1Agt	involves: 129S2/SvPas	color key
MP:0005450	abnormal energy expenditure	Ak1	Ak1^tm1Bew/Ak1^tm1Bew	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0002078	abnormal glucose homeostasis	Ak1	Ak1^tm1Bew/Ak1^tm1Bew	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0002123	abnormal hematopoiesis	Ifnar1	Ifnar1^tm1Pjh/Ifnar1^tm1Pjh	involves: 129S2/SvPas * BALB/c	color key
MP:0000716	abnormal immune system cell morphology	Impdh1	Impdh1^tm1Bmi/Impdh1^tm1Bmi	involves: 129/Sv * C57BL/6	color key
MP:0001845	abnormal inflammatory response	Ifnar1	Ifnar1^tm1Agt/Ifnar1^tm1Agt	involves: 129S2/SvPas	color key
MP:0002184	abnormal innervation	Nme1	Nme1^tm1Jyd/Nme1^tm1Jyd	involves: 129/Sv * C57BL/6	color key
MP:0008559	abnormal interferon-gamma secretion	Ifnar1	Ifnar1^tm1Agt/Ifnar1^tm1Agt	involves: 129S2/SvPas * 129S6/SvEvTac	color key
MP:0002136	abnormal kidney physiology	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0001882	abnormal lactation	Nme1	Nme1^tm1Jyd/Nme1^tm1Jyd	129-Nme1	color key
MP:0000598	abnormal liver morphology	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0000717	abnormal lymphocyte cell number	Impdh2	Impdh2^tm1Bmi/Impdh2⁺	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0002451	abnormal macrophage physiology	Ifnar1	Ifnar1^tm1Pjh/Ifnar1^tm1Pjh	involves: 129S2/SvPas * BALB/c	color key
MP:0002451	abnormal macrophage physiology	Ifnar1	Ifnar1^m1Btlr/Ifnar1^m1Btlr	C57BL/6J-Ifnar1	color key
MP:0005232	abnormal mesenteric lymph node morphology	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0002106	abnormal muscle physiology	Ak1	Ak1^tm1Bew/Ak1^tm1Bew	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0003806	abnormal nucleotide metabolism	Ak1	Ak1^tm1Bew/Ak1^tm1Bew	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0004982	abnormal osteoclast morphology	Ifnar1	Ifnar1^tm1Agt/Ifnar1^tm1Agt	B6.129S2-Ifnar1	color key
MP:0005025	abnormal response to infection	Ifnar1	Ifnar1^tm1Agt/Ifnar1^tm1Agt	B6.129S2-Ifnar1	color key
MP:0000613	abnormal salivary gland morphology	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0002651	abnormal sciatic nerve	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0000759	abnormal skeletal muscle morphology	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0000703	abnormal thymus morphology	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0000343	altered response to myocardial infarction	Ak1	Ak1^tm1Bew/Ak1^tm1Bew	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0001793	altered susceptibility to infection	Ifnar1	Ifnar1^tm1Agt/Ifnar1^tm1Agt	involves: 129S2/SvPas * C57BL/6	color key
MP:0003141	cardiac fibrosis	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0005542	corneal vascularization	Ifnar1	Ifnar1^tm1Agt/Ifnar1^tm1Agt	involves: 129S2/SvPas	color key
MP:0008045	decreased NK cell number	Ifnar1	Ifnar1^tm1Pjh/Ifnar1^tm1Pjh	B6.129S2-Ifnar1	color key
MP:0005095	decreased T cell proliferation	Impdh1	Impdh1^tm1Bmi/Impdh1^tm1Bmi	involves: 129/Sv * C57BL/6	color key
MP:0001262	decreased body weight	Nme1	Nme1^tm1Jyd/Nme1^tm1Jyd	involves: 129/Sv * C57BL/6	color key
MP:0001262	decreased body weight	Nme1	Nme1^tm1Jyd/Nme1^tm1Jyd	B6.129-Nme1	color key
MP:0001262	decreased body weight	Nme1	Nme1^tm1Jyd/Nme1^tm1Jyd	129-Nme1	color key
MP:0000063	decreased bone density	Ifnar1	Ifnar1^tm1Agt/Ifnar1^tm1Agt	B6.129S2-Ifnar1	color key
MP:0008563	decreased interferon-alpha secretion	Ifnar1	Ifnar1^tm1Agt/Ifnar1^tm1Agt	B6.129S2-Ifnar1	color key
MP:0008563	decreased interferon-alpha secretion	Ifnar1	Ifnar1^m1Btlr/Ifnar1^m1Btlr	C57BL/6J-Ifnar1	color key
MP:0008565	decreased interferon-beta secretion	Ifnar1	Ifnar1^tm1Agt/Ifnar1^tm1Agt	B6.129S2-Ifnar1	color key
MP:0008565	decreased interferon-beta secretion	Ifnar1	Ifnar1^m1Btlr/Ifnar1^m1Btlr	C57BL/6J-Ifnar1	color key
MP:0005517	decreased liver regeneration	Nme1	Nme1^tm1Jyd/Nme1^tm1Jyd	involves: 129/Sv * C57BL/6	color key
MP:0008479	decreased spleen white pulp amount	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0002705	dilated renal tubules	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0006204	embryonic lethality before implantation	Impdh2	Impdh2^tm1Bmi/Impdh2^tm1Bmi	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0005264	glomerulosclerosis	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0005070	impaired NK cell cytolysis	Ifnar1	Ifnar1^tm1Agt/Ifnar1^tm1Agt	involves: 129S2/SvPas	color key
MP:0005070	impaired NK cell cytolysis	Ifnar1	Ifnar1^tm1Agt/Ifnar1^tm1Agt	B6.129S2-Ifnar1	color key
MP:0005070	impaired NK cell cytolysis	Ifnar1	Ifnar1^tm1Pjh/Ifnar1^tm1Pjh	B6.129S2-Ifnar1	color key
MP:0008617	increased circulating interleukin-12 level	Ifnar1	Ifnar1^tm1Agt/Ifnar1^tm1Agt	involves: 129S2/SvPas * 129S6/SvEvTac	color key
MP:0004499	increased incidence of chemically-induced tumors	Ifnar1	Ifnar1^tm1Pjh/Ifnar1^tm1Pjh	B6.129S2-Ifnar1	color key
MP:0002021	increased incidence of induced tumors	Ifnar1	Ifnar1^tm1Pjh/Ifnar1^tm1Pjh	B6.129S2-Ifnar1	color key
MP:0002418	increased susceptibility to viral infection	Ifnar1	Ifnar1^tm1Agt/Ifnar1^tm1Agt	involves: 129S2/SvPas	color key
MP:0002418	increased susceptibility to viral infection	Ifnar1	Ifnar1^tm1Pjh/Ifnar1^tm1Pjh	involves: 129S2/SvPas * BALB/c	color key
MP:0002418	increased susceptibility to viral infection	Ifnar1	Ifnar1^tm1Agt/Ifnar1^tm1Agt	involves: 129S2/SvPas * BALB/c * C57BL/6 * SJL	color key
MP:0002418	increased susceptibility to viral infection	Ifnar1	Ifnar1^tm1Agt/Ifnar1^tm1Agt	involves: 129S2/SvPas * 129S6/SvEvTac	color key
MP:0002418	increased susceptibility to viral infection	Ifnar1	Ifnar1^m1Btlr/Ifnar1^m1Btlr	C57BL/6J-Ifnar1	color key
MP:0003721	increased tumor growth/size	Ifnar1	Ifnar1^tm1Agt/Ifnar1^tm1Agt	B6.129S2-Ifnar1	color key
MP:0003606	kidney failure	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0002022	lymphoma	Nme1	Nme1^tm1Jyd/Nme1^tm1Jyd	involves: 129/Sv * C57BL/6	color key
MP:0003718	maternal effect	Nme1	Nme1^tm1Jyd/Nme1^tm1Jyd	involves: 129/Sv * C57BL/6	color key
MP:0003718	maternal effect	Nme1	Nme1^tm1Jyd/Nme1^tm1Jyd	B6.129-Nme1	color key
MP:0001732	postnatal growth retardation	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0002082	postnatal lethality	Nme1	Nme1^tm1Jyd/Nme1^tm1Jyd	involves: 129/Sv * C57BL/6	color key
MP:0002082	postnatal lethality	Nme1	Nme1^tm1Jyd/Nme1^tm1Jyd	B6.129-Nme1	color key
MP:0002082	postnatal lethality	Nme1	Nme1^tm1Jyd/Nme1^tm1Jyd	129-Nme1	color key
MP:0002083	premature death	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key
MP:0005160	proteinuria	Rrm2b	Rrm2b^tm1Ynak/Rrm2b^tm1Ynak	involves: 129/Sv * C57BL/6J	color key