MGI MouseCyc MP annotations for PWY-2201

MGI MouseCyc MP annotations for PWY-2201: folate transformations

Roles of genes might be detected in a summary/comparison table of high level MP categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";

Compare annotations to MP categories for PWY-2201.

Entry indicates that gene is in this pathway.
Colored entries indicate MP annotation.

ID	Term	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2
MP:0005380	embryogenesis phenotype	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2
MP:0005378	growth/size phenotype	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2
MP:0005376	homeostasis/metabolism phenotype	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2
MP:0005374	lethality-prenatal/perinatal	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2
MP:0005372	life span-post-weaning/aging	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2
MP:0005371	limbs/digits/tail phenotype	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2
MP:0005370	liver/biliary system phenotype	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2
MP:0003631	nervous system phenotype	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2
MP:0005389	reproductive system phenotype	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2
MP:0005390	skeleton phenotype	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2
MP:0005393	skin/coat/nails phenotype	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2
MP:0005391	vision/eye phenotype	Gldc	Mthfd1	Mthfd1l	Mthfd2	Mthfr	Mthfs	Mthfsd	Mtr	Shmt1	Shmt2

Full set of annotations for PWY-2201

ID	Term	Mouse gene	Alleles	Background	Color Key
MP:0000886	abnormal cerebellar granule layer	Mthfr	Mthfr^tm1Rzn/Mthfr^tm1Rzn	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0005311	abnormal circulating amino acid level	Mtr	Mtr^tm1Lcb/Mtr⁺	129S/SvEv-Mtr	color key
MP:0005311	abnormal circulating amino acid level	Mtr	Mtr^tm1Lcb/Mtr⁺	involves: 129S/SvEv * Black Swiss	color key
MP:0005311	abnormal circulating amino acid level	Shmt1	Shmt1^tm1Stov/Shmt1^tm1Stov	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0005311	abnormal circulating amino acid level	Shmt1	Shmt1^tm1Stov/Shmt1⁺	involves: 129S7/SvEvBrd * C57BL/6	color key
MP:0006076	abnormal circulating homocysteine level	Mthfr	Mthfr^tm1Rzn/Mthfr^tm1Rzn	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0006076	abnormal circulating homocysteine level	Mthfr	Mthfr^tm1Rzn/Mthfr⁺	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0002118	abnormal lipid homeostasis	Mthfr	Mthfr^tm1Rzn/Mthfr^tm1Rzn	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0002118	abnormal lipid homeostasis	Mthfr	Mthfr^tm1Rzn/Mthfr⁺	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0000609	abnormal liver physiology	Shmt1	Shmt1^tm1.1Stov/Shmt1^tm1.1Stov	involves: 129S7/SvEvBrd * BALB/cJ * C57BL/6	color key
MP:0000609	abnormal liver physiology	Shmt1	Shmt1^tm1.1Stov/Shmt1⁺	129S/SvEv-Shmt1	color key
MP:0000609	abnormal liver physiology	Shmt1	Shmt1^tm1.1Stov/Shmt1^tm1.1Stov	129S/SvEv-Shmt1	color key
MP:0001262	decreased body weight	Mthfr	Mthfr^tm1Rzn/Mthfr^tm1Rzn	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0000884	delaminated Purkinje cell layer	Mthfr	Mthfr^tm1Rzn/Mthfr^tm1Rzn	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0001938	delayed sexual maturation	Mthfr	Mthfr^tm1Rzn/Mthfr^tm1Rzn	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0006207	embryonic lethality during organogenesis	Mtr	Mtr^tm1Lcb/Mtr^tm1Lcb	129S/SvEv-Mtr	color key
MP:0006207	embryonic lethality during organogenesis	Mtr	Mtr^tm1Lcb/Mtr^tm1Lcb	involves: 129S/SvEv * Black Swiss	color key
MP:0002750	exophthalmos	Mthfr	Mthfr^tm1Rzn/Mthfr^tm1Rzn	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0000585	kinked tail	Mthfr	Mthfr^tm1Rzn/Mthfr^tm1Rzn	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0000160	kyphosis	Mthfr	Mthfr^tm1Rzn/Mthfr^tm1Rzn	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0006208	lethality throughout fetal growth and development	Mthfd2	Mthfd2^tm1Rmk/Mthfd2^tm1Rmk	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0000603	pale liver	Mthfd2	Mthfd2^tm1Rmk/Mthfd2^tm1Rmk	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0001732	postnatal growth retardation	Mthfr	Mthfr^tm1Rzn/Mthfr^tm1Rzn	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0002083	premature death	Mthfr	Mthfr^tm1Rzn/Mthfr^tm1Rzn	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0001698	reduced embryo size	Mthfd2	Mthfd2^tm1Rmk/Mthfd2^tm1Rmk	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0001921	reduced fertility	Mthfd1	Mthfd1^neut2/Mthfd1^neut2	involves: C57BL/6JAnl	color key
MP:0000592	short tail	Mthfr	Mthfr^tm1Rzn/Mthfr^tm1Rzn	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0000852	small cerebellum	Mthfr	Mthfr^tm1Rzn/Mthfr^tm1Rzn	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0000601	small liver	Mthfd2	Mthfd2^tm1Rmk/Mthfd2^tm1Rmk	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key
MP:0000416	sparse hair	Mthfr	Mthfr^tm1Rzn/Mthfr^tm1Rzn	involves: 129S1/Sv * 129X1/SvJ * BALB/c	color key