MGI MouseCyc MP annotations for PWY3DJ-11470

MGI MouseCyc MP annotations for PWY3DJ-11470: sphingosine and sphingosine-1-phosphate metabolism

Roles of genes might be detected in a summary/comparison table of high level MP categories.
Complete table of the annotations represented in this image is provided below.
Graph is also available as SVG (requires plug-in)

Gray arrows indicate "is_a";
Blue arrows indicate "part_of";

Compare annotations to MP categories for PWY3DJ-11470.

Entry indicates that gene is in this pathway.
Colored entries indicate MP annotation.

ID	Term	Asah1	Asah2	Asah3	Ptgr1	Sgpl1	Sgpp1	Sphk1	Sphk2
MP:0005385	cardiovascular system phenotype	Asah1	Asah2	Asah3	Ptgr1	Sgpl1	Sgpp1	Sphk1	Sphk2
MP:0005384	cellular phenotype	Asah1	Asah2	Asah3	Ptgr1	Sgpl1	Sgpp1	Sphk1	Sphk2
MP:0005382	craniofacial phenotype	Asah1	Asah2	Asah3	Ptgr1	Sgpl1	Sgpp1	Sphk1	Sphk2
MP:0005381	digestive/alimentary phenotype	Asah1	Asah2	Asah3	Ptgr1	Sgpl1	Sgpp1	Sphk1	Sphk2
MP:0005379	endocrine/exocrine gland phenotype	Asah1	Asah2	Asah3	Ptgr1	Sgpl1	Sgpp1	Sphk1	Sphk2
MP:0005378	growth/size phenotype	Asah1	Asah2	Asah3	Ptgr1	Sgpl1	Sgpp1	Sphk1	Sphk2
MP:0005397	hematopoietic system phenotype	Asah1	Asah2	Asah3	Ptgr1	Sgpl1	Sgpp1	Sphk1	Sphk2
MP:0005376	homeostasis/metabolism phenotype	Asah1	Asah2	Asah3	Ptgr1	Sgpl1	Sgpp1	Sphk1	Sphk2
MP:0005387	immune system phenotype	Asah1	Asah2	Asah3	Ptgr1	Sgpl1	Sgpp1	Sphk1	Sphk2
MP:0005374	lethality-prenatal/perinatal	Asah1	Asah2	Asah3	Ptgr1	Sgpl1	Sgpp1	Sphk1	Sphk2
MP:0005372	life span-post-weaning/aging	Asah1	Asah2	Asah3	Ptgr1	Sgpl1	Sgpp1	Sphk1	Sphk2
MP:0005370	liver/biliary system phenotype	Asah1	Asah2	Asah3	Ptgr1	Sgpl1	Sgpp1	Sphk1	Sphk2
MP:0005369	muscle phenotype	Asah1	Asah2	Asah3	Ptgr1	Sgpl1	Sgpp1	Sphk1	Sphk2
MP:0002873	normal phenotype	Asah1	Asah2	Asah3	Ptgr1	Sgpl1	Sgpp1	Sphk1	Sphk2
MP:0005367	renal/urinary system phenotype	Asah1	Asah2	Asah3	Ptgr1	Sgpl1	Sgpp1	Sphk1	Sphk2
MP:0005389	reproductive system phenotype	Asah1	Asah2	Asah3	Ptgr1	Sgpl1	Sgpp1	Sphk1	Sphk2
MP:0005390	skeleton phenotype	Asah1	Asah2	Asah3	Ptgr1	Sgpl1	Sgpp1	Sphk1	Sphk2

Full set of annotations for PWY3DJ-11470

ID	Term	Mouse gene	Alleles	Background	Color Key
MP:0005536	Leydig cell hypoplasia	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)	color key
MP:0002459	abnormal B cell physiology	Sphk2	Sphk2^tm1Npa/Sphk2^tm1Npa	BALB/c-Sphk2	color key
MP:0000076	abnormal calvaria morphology	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	involves: 129S4/SvJaeSor	color key
MP:0003091	abnormal cell migration	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	involves: 129S4/SvJaeSor	color key
MP:0000107	abnormal frontal bone morphology	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	involves: 129S4/SvJaeSor	color key
MP:0002135	abnormal kidney morphology	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	involves: 129S4/SvJaeSor	color key
MP:0002136	abnormal kidney physiology	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	involves: 129S4/SvJaeSor	color key
MP:0002118	abnormal lipid homeostasis	Asah1	Asah1^tm1Esc/Asah1⁺	involves: 129S1/Sv * C57BL/6	color key
MP:0001547	abnormal lipid level	Asah2	Asah2^tm1Rlp/Asah2^tm1Rlp	involves: 129S6/SvEvTac * C57BL/6	color key
MP:0000598	abnormal liver morphology	Asah1	Asah1^tm1Esc/Asah1⁺	involves: 129S1/Sv * C57BL/6	color key
MP:0004215	abnormal myocardial fiber physiology	Sphk1	Sphk1^tm1.1Cgh/Sphk1^tm1.1Cgh	involves: 129S4/SvJae * C57BL/6	color key
MP:0008871	abnormal ovarian follicle number	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)	color key
MP:0001126	abnormal ovary morphology	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)	color key
MP:0003755	abnormal palate morphology	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	involves: 129S4/SvJaeSor	color key
MP:0004537	abnormal palatine shelf	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	involves: 129S4/SvJaeSor	color key
MP:0004448	abnormal presphenoid bone morphology	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	involves: 129S4/SvJaeSor	color key
MP:0002124	abnormal red blood cell	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	involves: 129S4/SvJaeSor	color key
MP:0005325	abnormal renal glomerulus morphology	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	involves: 129S4/SvJaeSor	color key
MP:0005508	abnormal skeleton morphology	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	involves: 129S4/SvJaeSor	color key
MP:0000767	abnormal smooth muscle morphology	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	involves: 129S4/SvJaeSor	color key
MP:0006380	abnormal spermatid morphology	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)	color key
MP:0006379	abnormal spermatocyte morphology	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)	color key
MP:0001156	abnormal spermatogenesis	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)	color key
MP:0000157	abnormal sternum morphology	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	involves: 129S4/SvJaeSor	color key
MP:0006418	abnormal testis cord formation	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)	color key
MP:0001146	abnormal testis morphology	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)	color key
MP:0005592	abnormal vascular smooth muscle morphology	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)	color key
MP:0001614	abnormal vasculature	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	involves: 129S4/SvJaeSor	color key
MP:0000137	abnormal vertebrae morphology	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	involves: 129S4/SvJaeSor	color key
MP:0004599	abnormal vertebral arch morphology	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	involves: 129S4/SvJaeSor	color key
MP:0001134	absent corpus luteum	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)	color key
MP:0001577	anemia	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	involves: 129S4/SvJaeSor	color key
MP:0008869	anovulation	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)	color key
MP:0008146	asymmetric rib-sternum attachment	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	involves: 129S4/SvJaeSor	color key
MP:0001262	decreased body weight	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	involves: 129S4/SvJaeSor	color key
MP:0005181	decreased circulating estradiol level	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)	color key
MP:0002780	decreased circulating testosterone level	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)	color key
MP:0002875	decreased erythrocyte cell number	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	involves: 129S4/SvJaeSor	color key
MP:0000208	decreased hematocrit	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	involves: 129S4/SvJaeSor	color key
MP:0002874	decreased hemoglobin content	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	involves: 129S4/SvJaeSor	color key
MP:0008874	decreased sensitivity to xenobiotics	Sphk2	Sphk2^{Gt(NPX039)Byg}/Sphk2^{Gt(NPX039)Byg}	involves: 129P2/OlaHsd * C57BL/6	color key
MP:0006206	embryonic lethality before turning of embryo	Asah1	Asah1^tm1Esc/Asah1^tm1Esc	involves: 129S1/Sv * C57BL/6	color key
MP:0001926	female infertility	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)	color key
MP:0001914	hemorrhage	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	involves: 129S4/SvJaeSor	color key
MP:0005014	increased B cell number	Sphk1	Sphk1^tm1Npa/Sphk1^tm1Npa	BALB/c-Sphk1	color key
MP:0005014	increased B cell number	Sphk2	Sphk2^tm1Npa/Sphk2^tm1Npa	BALB/c-Sphk2	color key
MP:0005565	increased blood urea nitrogen level	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	involves: 129S4/SvJaeSor	color key
MP:0001859	kidney inflammation	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	involves: 129S4/SvJaeSor	color key
MP:0001925	male infertility	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)	color key
MP:0002169	no abnormal phenotype detected	Sphk1	Sphk1^tm1Rlp/Sphk1^tm1Rlp	involves: 129S6/SvEvTac * C57BL/6	color key
MP:0002169	no abnormal phenotype detected	Sphk2	Sphk2^tm1Rlp/Sphk2^tm1Rlp	involves: C57BL/6	color key
MP:0004969	pale kidney	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	involves: 129S4/SvJaeSor	color key
MP:0000603	pale liver	Asah1	Asah1^tm1Esc/Asah1⁺	involves: 129S1/Sv * C57BL/6	color key
MP:0005097	polychromatophilia	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	involves: 129S4/SvJaeSor	color key
MP:0001732	postnatal growth retardation	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	involves: 129S4/SvJaeSor	color key
MP:0002083	premature death	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	involves: 129S4/SvJaeSor	color key
MP:0002989	small kidney	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	involves: 129S4/SvJaeSor	color key
MP:0001127	small ovary	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)	color key
MP:0001147	small testis	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)	color key
MP:0001121	uterus hypoplasia	Sgpl1	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}	either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)	color key